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Title   유방암의 종양표식자로서 CA 15-3 와 CEA 의 비교 ( Comparison of CA 15-3 with CEA as Tumor Marker of Breast Cancer )
Publicationinfo   1992 Jan; 024(06): 829-834.
Key_word   CA 15-3, CEA(carcinoembryonic antigen), Breast cancer
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Abstract   There has been strong need for a simple, specific and sensitive tumor marker in diagnosing and following up the patients with breast cancer. Many markers have been developed and in- vestigated, but CEA and CA 15-3 are two of the most widely used tumor markers for this dis- ease#. In this study, we compared the CA 15-3 with CEA. Clinical analysis was performed on 67 patients diagnosed with breast cancer who were admitted to KangNam St.Marys Hospital, Seoul, Korea, from Feb. 1985 to Apr. 1990. The results were as follows; 1) For groups with no evidence of metastatic breast cancer, there was no difference between the average value of CEA and CA 15-3 detected 2) All(100%) of the metastatic cases showed the significantly elevated level of CA 15-3, compared to 56% that showed CEA e1evation Our results indicate that CEA and CA 15-3 are not suitable for screening and diagnosis of pa- tients with breast cancer, since they are not elevated in nonmetatatic primary breast cancer patient. Howerer, CA 15-3 is superior to CEA in detecting recurrent or metastatic breast cancer.
저 자   문성도(Seong Do Moon),정상설(Sang Seol Jung),김인철(In Chul Kim),이덕섭(Deog Seob Lee)